HCID 12467904, compound → HCID 20292145, compound

HRID 1413587Notes

Reaction equation

HRID 1413587 reaction equation
[C:1]([N:4]([CH2:13][CH2:14][C:15]([OH:17])=O)[C:5]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:6]=1[CH3:12])(=[O:3])[CH3:2].[CH3:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([NH:26][CH2:27][CH2:28][CH2:29][C:30]([O:32][CH3:33])=[O:31])=[CH:22][CH:21]=1>>[C:1]([N:4]([CH2:13][CH2:14][C:15]([N:26]([CH2:27][CH2:28][CH2:29][C:30]([O:32][CH3:33])=[O:31])[C:23]1[CH:22]=[CH:21][C:20]([O:19][CH3:18])=[CH:25][CH:24]=1)=[O:17])[C:5]1[C:6]([CH3:12])=[CH:7][CH:8]=[CH:9][C:10]=1[CH3:11])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 12467904HCID 12467904, compoundHCID 20292110HCID 20292110, compound

Product 1

HCID 20292145HCID 20292145, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-acetyl-3-(2,6-dimethylanilino)propionic acid and methyl 4-(p-anisidino)butyrate and suitable processing produces methyl N-[N-acetyl-3-(2,6-dimethylanilino)propionyl]-4-(p-anisidino)butyrate (oil), saponification of which and processing of the reaction product yields N-[N-acetyl-3-(2,6-dimethylanilino)propionyl]-4-(p-anisidino)butyric acid (M.P. 90° to 92°).

Sources & evidence

ORD record
ord-1eb44eddadd844fd91f220168d3c0d50
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

Loading…