HCID 20292110, compound → HCID 20292103, compound

HRID 1413589Notes

Reaction equation

HRID 1413589 reaction equation
[C:1]([N:4]([CH2:13][CH2:14][C:15]([OH:17])=O)[C:5]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:6]=1[CH3:12])(=[O:3])[CH3:2].[CH2:18]([C:20]1[CH:34]=[CH:33][CH:32]=[C:31]([CH3:35])[C:21]=1[NH:22][CH2:23][CH2:24][CH2:25][C:26]([O:28][CH2:29][CH3:30])=[O:27])[CH3:19]>>[C:1]([N:4]([CH2:13][CH2:14][C:15]([N:22]([CH2:23][CH2:24][CH2:25][C:26]([O:28][CH2:29][CH3:30])=[O:27])[C:21]1[C:31]([CH3:35])=[CH:32][CH:33]=[CH:34][C:20]=1[CH2:18][CH3:19])=[O:17])[C:5]1[C:6]([CH3:12])=[CH:7][CH:8]=[CH:9][C:10]=1[CH3:11])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 20292110HCID 20292110, compoundHCID 20292193HCID 20292193, compound

Product 1

HCID 20292103HCID 20292103, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-acetyl-3-(2,6-dimethylanilino)propionic acid and ethyl 4-(2-ethyl-6-methylanilino)butyrate and suitable processing produces ethyl N-[N-acetyl-3-(2,6-dimethylanilino)propionyl]-4-(2-ethyl-6-methylanilino)butyrate (oil), saponification of which and processing of the reaction product yields N-[N-acetyl-3-(2,6-dimethylanilino)propionyl]-4-(2-ethyl-6-methylanilino)butyric acid (M.P. 139° to 141°).

Sources & evidence

ORD record
ord-4445e5b603e14b9a9ce0de5bbe5ace9f
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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