HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-(2,6-dimethylanilino)butyrate → ethyl N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]-4-(2,6-dimethylanilino)butyrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-(2,6-dimethylanilino)butyrate | HCID 20292063 | — |
| Reactant | N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetic acid | HCID 20292207 | — |
| Product | ethyl N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]-4-(2,6-dimethylanilino)butyrate | HCID 20292231 | — |
Reaction Steps
Analogously to Example 1, by using equivalent quantities, reacting N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetic acid and ethyl 4-(2,6-dimethylanilino)butyrate and suitable processing produces ethyl N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]-4-(2,6-dimethylanilino)butyrate (M.P. 150° to 151°), saponification of which and processing of the reaction product yields N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]-4-(2,6-dimethylanilino) butyric acid (M.P. 214° to 216°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04250183 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-53de29a8e48f432caeb16d72f77adf74 |
| Source note | uspto-grants-1981_02 |