HCID 12467904, compound → HCID 20292142, compound

HRID 1413591Notes

Reaction equation

HRID 1413591 reaction equation
[Cl:1][C:2]1[CH:22]=[CH:21][C:5]([C:6]([N:8]([CH2:17][C:18]([OH:20])=O)[C:9]2[CH:16]=[CH:15][C:12]([O:13][CH3:14])=[CH:11][CH:10]=2)=[O:7])=[CH:4][CH:3]=1.[CH3:23][O:24][C:25]1[CH:30]=[CH:29][C:28]([NH:31][CH2:32][CH2:33][CH2:34][C:35]([O:37][CH3:38])=[O:36])=[CH:27][CH:26]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([N:8]([CH2:17][C:18]([N:31]([CH2:32][CH2:33][CH2:34][C:35]([O:37][CH3:38])=[O:36])[C:28]2[CH:27]=[CH:26][C:25]([O:24][CH3:23])=[CH:30][CH:29]=2)=[O:20])[C:9]2[CH:10]=[CH:11][C:12]([O:13][CH3:14])=[CH:15][CH:16]=2)=[O:7])=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 12467904HCID 12467904, compoundHCID 20292119HCID 20292119, compound

Product 1

HCID 20292142HCID 20292142, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(p-chlorobenzoyl)-2-(p-anisidino)acetic acid and methyl 4-(p-anisidino)butyrate and suitable processing produces methyl N-[N-(p-chlorobenzoyl)-2-(p-anisidino)acetyl]-4-(p-anisidino)butyrate (oil), saponification of which and processing of the reaction product yields N-[N-(p-chlorobenzoyl)-2-(p-anisidino)acetyl]-4-(p-anisidino)butyric acid (M.P. 105° to 108°).

Sources & evidence

ORD record
ord-eef16d1830064fe2b124992253919a3b
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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