HCID 12467904, compound → HCID 20292071, compound

HRID 1413592Notes

Reaction equation

HRID 1413592 reaction equation
[C:1]([N:4]([CH2:13][C:14]([OH:16])=O)[C:5]1[CH:12]=[CH:11][C:8]([O:9][CH3:10])=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[CH3:17][O:18][C:19]1[CH:24]=[CH:23][C:22]([NH:25][CH2:26][CH2:27][CH2:28][C:29]([O:31][CH3:32])=[O:30])=[CH:21][CH:20]=1>>[C:1]([N:4]([CH2:13][C:14]([N:25]([CH2:26][CH2:27][CH2:28][C:29]([O:31][CH3:32])=[O:30])[C:22]1[CH:21]=[CH:20][C:19]([O:18][CH3:17])=[CH:24][CH:23]=1)=[O:16])[C:5]1[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[CH:11][CH:12]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 12467904HCID 12467904, compoundHCID 14484962HCID 14484962, compound

Product 1

HCID 20292071HCID 20292071, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(acetyl)-2-(p-anisidino)acetic acid and methyl 4-(p-anisidino)butyrate and suitable processing produces methyl N-[N-(acetyl)-2-(p-anisidino)acetyl]-4-(p-anisidino)butyrate (oil), saponification of which and processing of the reaction product yields N-[N-acetyl-2-(p-anisidino)acetyl]-4-(p-anisidino)butyric acid (M.P. 97° to 100°).

Sources & evidence

ORD record
ord-3bc2bbfd0c59432786512403ca4cb1aa
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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