HCID 12467904, compound → HCID 20292143, compound

HRID 1413593Notes

Reaction equation

HRID 1413593 reaction equation
[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([C:6]([N:8]([CH:17]([CH3:21])[C:18](O)=[O:19])[C:9]2[CH:16]=[CH:15][C:12]([O:13][CH3:14])=[CH:11][CH:10]=2)=[O:7])=[CH:4][CH:3]=1.[CH3:24][O:25][C:26]1[CH:31]=[CH:30][C:29]([NH:32][CH2:33][CH2:34][CH2:35][C:36]([O:38][CH3:39])=[O:37])=[CH:28][CH:27]=1>>[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([C:6]([N:8]([CH:17]([CH3:21])[C:18]([N:32]([CH2:33][CH2:34][CH2:35][C:36]([O:38][CH3:39])=[O:37])[C:29]2[CH:28]=[CH:27][C:26]([O:25][CH3:24])=[CH:31][CH:30]=2)=[O:19])[C:9]2[CH:10]=[CH:11][C:12]([O:13][CH3:14])=[CH:15][CH:16]=2)=[O:7])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 12467904HCID 12467904, compoundHCID 20292113HCID 20292113, compound

Product 1

HCID 20292143HCID 20292143, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(p-chlorobenzoyl)-2-(p-anisidino)propionic acid and methyl 4-(p-anisidino)butyrate and suitable processing produces methyl N-[N-(p-chlorobenzoyl)-2-(p-anisidino)propionyl]-4-(p-anisidino)butyrate (oil), saponification of which and processing of the reaction product yields N-[N-(p-chlorobenzoyl)-2-(p-anisidino)propionyl]-4-(p-anisidino)butyric acid (M.P. 135° to 137°).

Sources & evidence

ORD record
ord-7ac35d06b18d40eaa4f3c4d11bfcbe69
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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