HCID 12467904, compound → HCID 20292198, compound

HRID 1413594Notes

Reaction equation

HRID 1413594 reaction equation
[Cl:1][C:2]1[CH:23]=[C:22]([Cl:24])[CH:21]=[CH:20][C:3]=1[C:4]([N:6]([CH:15]([CH3:19])[C:16](O)=[O:17])[C:7]1[CH:14]=[CH:13][C:10]([O:11][CH3:12])=[CH:9][CH:8]=1)=[O:5].[CH3:25][O:26][C:27]1[CH:32]=[CH:31][C:30]([NH:33][CH2:34][CH2:35][CH2:36][C:37]([O:39][CH3:40])=[O:38])=[CH:29][CH:28]=1>>[Cl:1][C:2]1[CH:23]=[C:22]([Cl:24])[CH:21]=[CH:20][C:3]=1[C:4]([N:6]([CH:15]([CH3:19])[C:16]([N:33]([CH2:34][CH2:35][CH2:36][C:37]([O:39][CH3:40])=[O:38])[C:30]1[CH:29]=[CH:28][C:27]([O:26][CH3:25])=[CH:32][CH:31]=1)=[O:17])[C:7]1[CH:8]=[CH:9][C:10]([O:11][CH3:12])=[CH:13][CH:14]=1)=[O:5]

Participants

3

Reactant 2

HCID 12467904HCID 12467904, compoundHCID 20292221HCID 20292221, compound

Product 1

HCID 20292198HCID 20292198, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(2,4-dichlorobenzoyl)-2-(p-anisidino)propionic acid and methyl 4-(p-anisidino)butyrate and suitable processing produces methyl N-[N-(2,4-dichlorobenzoyl)-2-(p-anisidino)propionyl]-4-(p-anisidino)butyrate (oil), saponification of which and processing of the reaction product yields N-[N-(2,4-dichlorobenzoyl)-2-(p-anisidino)propionyl]-4-(p-anisidino)butyric acid (M.P. 159° to 160°).

Sources & evidence

ORD record
ord-61c7a375f0f7413fa85fbd6b375506db
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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