HCID 12390789, compound → HCID 20292139, compound

HRID 1413595Notes

Reaction equation

HRID 1413595 reaction equation
[C:1]([N:4]([CH:13]([CH3:17])[C:14]([OH:16])=O)[C:5]1[CH:12]=[CH:11][C:8]([O:9][CH3:10])=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[CH3:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([NH:26][CH2:27][CH2:28][CH2:29][C:30]([O:32][CH3:33])=[O:31])=[CH:22][CH:21]=1>>[C:1]([N:4]([CH:13]([CH3:17])[C:14]([N:26]([CH2:27][CH2:28][CH2:29][C:30]([O:32][CH3:33])=[O:31])[C:23]1[CH:22]=[CH:21][C:20]([O:19][CH3:18])=[CH:25][CH:24]=1)=[O:16])[C:5]1[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[CH:11][CH:12]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 12390789HCID 12390789, compoundHCID 12467904HCID 12467904, compound

Product 1

HCID 20292139HCID 20292139, compound

Procedure

Analogously toExample 1, by using equivalent quantities, reacting N-acetyl-2-(p-anisidino)propionic acid and methyl 4-(p-anisidino)butyrate and suitable processing produces methyl N-[N-acetyl-2-(p-anisidino)propionyl]-4-(p-anisidino)butyrate (M.P. 111° to 113°), saponification of which and processing of the reaction produce yields N-[N-acetyl-2-(p-anisidino)propionyl]-4-(p-anisidino)butyric acid (M.P. 155° to 157°).

Sources & evidence

ORD record
ord-4626cea3b8314bc08d5aabc814df1ad7
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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