HCID 12467904, compound → HCID 20292127, compound

HRID 1413596Notes

Reaction equation

HRID 1413596 reaction equation
[F:1][C:2]([F:26])([F:25])[C:3]1[CH:4]=[C:5]([CH:22]=[CH:23][CH:24]=1)[C:6]([N:8]([CH:17]([CH3:21])[C:18](O)=[O:19])[C:9]1[CH:16]=[CH:15][C:12]([O:13][CH3:14])=[CH:11][CH:10]=1)=[O:7].[CH3:27][O:28][C:29]1[CH:34]=[CH:33][C:32]([NH:35][CH2:36][CH2:37][CH2:38][C:39]([O:41][CH3:42])=[O:40])=[CH:31][CH:30]=1>>[F:1][C:2]([F:25])([F:26])[C:3]1[CH:4]=[C:5]([CH:22]=[CH:23][CH:24]=1)[C:6]([N:8]([CH:17]([CH3:21])[C:18]([N:35]([CH2:36][CH2:37][CH2:38][C:39]([O:41][CH3:42])=[O:40])[C:32]1[CH:31]=[CH:30][C:29]([O:28][CH3:27])=[CH:34][CH:33]=1)=[O:19])[C:9]1[CH:10]=[CH:11][C:12]([O:13][CH3:14])=[CH:15][CH:16]=1)=[O:7]

Participants

3

Reactant 2

HCID 12467904HCID 12467904, compoundHCID 20292157HCID 20292157, compound

Product 1

HCID 20292127HCID 20292127, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(m-trifluoromethylbenzoyl)-2-(p-anisidino)propionic acid and methyl 4-(p-anisidino)butyrate and suitable processing produces methyl N-[N-(m-trifluoromethylbenzoyl)-2-(p-anisidino)propionyl]-4-(p-anisidino)butyrate (oil), saponification of which and processing of the reaction product yields N-[N-(m-trifluoromethylbenzoyl)2-(p-anisidino)propionyl]-4-(p-anisidino)butyric acid (M.P. 119° to 121°).

Sources & evidence

ORD record
ord-552fb5b82fd94ff8912d469d89d9a0ed
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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