HCID 695332, compound → HCID 22814605, compound

HRID 1413598Notes

Reaction equation

HRID 1413598 reaction equation
[Cl:1][C:2]1[CH:21]=[CH:20][C:5]([C:6]([NH:8][C@H:9]([C:17]([OH:19])=O)[CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:7])=[CH:4][CH:3]=1.[CH3:22][O:23][C:24]1[CH:29]=[CH:28][C:27]([NH:30][CH2:31][CH2:32][CH2:33][C:34]([O:36][CH3:37])=[O:35])=[CH:26][CH:25]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([NH:8][C@H:9]([C:17]([N:30]([CH2:31][CH2:32][CH2:33][C:34]([O:36][CH3:37])=[O:35])[C:27]2[CH:26]=[CH:25][C:24]([O:23][CH3:22])=[CH:29][CH:28]=2)=[O:19])[CH2:10][C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)=[O:7])=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 695332HCID 695332, compoundHCID 12467904HCID 12467904, compound

Product 1

HCID 22814605HCID 22814605, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(p-chlorobenzoyl)phenylalanine and methyl 4-(p-anisidino)butyrate and suitable processing produces methyl N-[N-(p-chlorobenzoyl)phenylalanyl]-4-(p-anisidino)butyrate (oil), saponification of which and processing of the reaction product yields N-[N-(p-chlorobenzoyl)phenylalanyl]-4-(p-anisidino)butyric acid (M.P. 163° to 165°).

Sources & evidence

ORD record
ord-e9b1cf24b42c4c3c8cdd19681adb4905
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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