Ethyl 3-aminopropanoate → HCID 20292232, compound

HRID 1413599Notes

Reaction equation

HRID 1413599 reaction equation
[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([C:6]([N:8]([CH2:17][CH2:18][C:19](O)=[O:20])[C:9]2[CH:16]=[CH:15][C:12]([O:13][CH3:14])=[CH:11][CH:10]=2)=[O:7])=[CH:4][CH:3]=1.[NH2:24][CH2:25][CH2:26][C:27]([O:29][CH2:30][CH3:31])=[O:28]>>[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([C:6]([N:8]([CH2:17][CH2:18][C:19]([NH:24][CH2:25][CH2:26][C:27]([O:29][CH2:30][CH3:31])=[O:28])=[O:20])[C:9]2[CH:16]=[CH:15][C:12]([O:13][CH3:14])=[CH:11][CH:10]=2)=[O:7])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 419889Ethyl 3-aminopropanoateHCID 20292098HCID 20292098, compound

Product 1

HCID 20292232HCID 20292232, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(p-chlorobenzoyl)-3-(p-anisidino)propionic acid and ethyl 3-aminopropionate and suitable processing produces ethyl N-[N-(p-chlorobenzoyl)-3-(p-anisidino)propionyl]-3-aminopropionate (oil), saponification of which and processing of the reaction product yields N-[N-(p-chlorobenzoyl)-3-(p-anisidino)propionyl]-3-aminopropionic acid (M.P. 171° to 172°).

Sources & evidence

ORD record
ord-53f43edad67a4963ad1c37a86fd2364b
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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