Butyric acid, 4-(p-chloro-N-2,6-xylylbenzamido)- → HCID 20292241, compound

HRID 1413602Notes

Reaction equation

HRID 1413602 reaction equation
[Cl:1][C:2]1[CH:24]=[CH:23][C:5]([C:6]([N:8]([CH2:17][CH2:18][CH2:19][C:20]([OH:22])=O)[C:9]2[C:14]([CH3:15])=[CH:13][CH:12]=[CH:11][C:10]=2[CH3:16])=[O:7])=[CH:4][CH:3]=1.[NH:25]([CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])[CH3:26]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([N:8]([CH2:17][CH2:18][CH2:19][C:20]([N:25]([CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])[CH3:26])=[O:22])[C:9]2[C:14]([CH3:15])=[CH:13][CH:12]=[CH:11][C:10]=2[CH3:16])=[O:7])=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 35383Butyric acid, 4-(p-chloro-N-2,6-xylylbenzamido)-HCID 95849Glycine, N-methyl-, ethyl ester

Product 1

HCID 20292241HCID 20292241, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(p-chlorobenzoyl)-4-(2,6-dimethylanilino)butyric acid and ethyl sarcosinate and suitable processing produces ethyl N-[N-(p-chlorobenzoyl)-4-(2,6-dimethylanilino)butyryl]sarcosinate (oil), saponification of which and processing of the reaction product yields N-[N-(p-chlorobenzoyl)-4-(2,6-dimethylanilino)butyryl]sarcosine (M.P. 103° to 105°).

Sources & evidence

ORD record
ord-690faac216374cfda3328331ade648ec
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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