Glycine, N-methyl-, ethyl ester → HCID 20292185, compound

HRID 1413606Notes

Reaction equation

HRID 1413606 reaction equation
[Cl:1][C:2]1[CH:22]=[CH:21][C:5]([C:6]([N:8]([CH2:17][C:18]([OH:20])=O)[C:9]2[CH:16]=[CH:15][C:12]([O:13][CH3:14])=[CH:11][CH:10]=2)=[O:7])=[CH:4][CH:3]=1.[NH:23]([CH2:25][C:26]([O:28][CH2:29][CH3:30])=[O:27])[CH3:24]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([N:8]([CH2:17][C:18]([N:23]([CH2:25][C:26]([O:28][CH2:29][CH3:30])=[O:27])[CH3:24])=[O:20])[C:9]2[CH:10]=[CH:11][C:12]([O:13][CH3:14])=[CH:15][CH:16]=2)=[O:7])=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 95849Glycine, N-methyl-, ethyl esterHCID 20292119HCID 20292119, compound

Product 1

HCID 20292185HCID 20292185, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(p-chlorobenzoyl)-2-(p-anisidino) acetic acid and ethyl sarcosinate and suitable processing produces ethyl N-[N-(p-chlorobenzoyl)-2-(p-anisidino)acetyl]sarcosinate (oil), saponification of which and processing of the reaction product yields N-[N-(p-chlorobenzoyl)-2-(p-anisidino)acetyl]sarcosine (M.P. 146° to 148°).

Sources & evidence

ORD record
ord-3f429b7e7b66478394d06c87750c4006
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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