HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine ethyl ester → ethyl N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]glycinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine ethyl ester | HCID 12176 | — |
| Reactant | N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetic acid | HCID 20292207 | — |
| Product | ethyl N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]glycinate | HCID 20292235 | — |
Reaction Steps
Analogously to Example 1, by using equivalent quantities, reacting N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetic acid and ethyl glycinate and suitable processing produces ethyl N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]glycinate (M.P. 127° to 129°), saponification of which and processing of the reaction product yields N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]glycine (M.P. 200° to 201°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04250183 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-4f52d250c8de4a4f931fe5318e277b79 |
| Source note | uspto-grants-1981_02 |