HCID 12220642, compound → HCID 20292074, compound

HRID 1413612Notes

Reaction equation

HRID 1413612 reaction equation
[C:1]([N:5]([CH2:14][CH2:15][CH2:16][C:17]([OH:19])=O)[C:6]1[C:11]([CH3:12])=[CH:10][CH:9]=[CH:8][C:7]=1[CH3:13])(=[O:4])[CH2:2][CH3:3].[CH2:20]([NH:27][CH2:28][CH2:29][CH2:30][C:31]([O:33][CH2:34][CH3:35])=[O:32])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[C:1]([N:5]([CH2:14][CH2:15][CH2:16][C:17]([N:27]([CH2:20][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)[CH2:28][CH2:29][CH2:30][C:31]([O:33][CH2:34][CH3:35])=[O:32])=[O:19])[C:6]1[C:7]([CH3:13])=[CH:8][CH:9]=[CH:10][C:11]=1[CH3:12])(=[O:4])[CH2:2][CH3:3]

Participants

3

Reactant 2

HCID 12220642HCID 12220642, compoundHCID 54573939HCID 54573939, compound

Product 1

HCID 20292074HCID 20292074, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-propionyl-4-(2,6-dimethylanilino)butyric acid and ethyl 4-(benzylamino)butyrate and suitable processing produces ethyl N-[N-propionyl-4-(2,6-dimethylanilino)butyryl]-4-(benzylamino)butyrate (oil), saponification of which and processing of the reaction product yields N-[N-propionyl-4-(2,6-dimethylanilino)butyryl]-4-(benzylamino)butyric acid (oil).

Sources & evidence

ORD record
ord-a6bf5d1117d0413a905902db8e2c6021
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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