Potassium Hydroxide → HCID 22814607, compound

HRID 1413627Notes

Reaction equation

HRID 1413627 reaction equation
[C:1]([N:4]([CH:13]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10](O)=[O:11])(=[O:3])[CH3:2].[NH2:26][C@H:27]([C:30]([O:32]CC)=[O:31])[CH2:28][OH:29].[OH-].[K+]>C(O)C>[C:1]([N:4]([CH:13]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([NH:26][C@H:27]([C:30]([OH:32])=[O:31])[CH2:28][OH:29])=[O:11])(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 2724186Ethyl serinateHCID 20292151HCID 20292151, compound

Product 1

HCID 22814607HCID 22814607, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-acetyl-6-benzhydrylaminocaproic acid and ethyl L-serinate and suitable processing, dissolving the evaporation residue in ethanol, adding an ethanolic solution of potassium hydroxide, stirring for 12 hours at room temperature and further processing yields N-(N-acetyl-6-benzhydrylaminohexanoyl)-L-serine.

Sources & evidence

ORD record
ord-f3a478522b024b128c9c8a5554c0c05d
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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