Potassium Hydroxide → HCID 20292149, compound

HRID 1413634Notes

Reaction equation

HRID 1413634 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([N:8]([CH:17]([CH3:21])[C:18]([OH:20])=O)[C:9]1[CH:16]=[CH:15][C:12]([O:13][CH3:14])=[CH:11][CH:10]=1)=[O:7].[C:22]1([CH:28]([NH:30][CH2:31][CH2:32][CH2:33][C:34]([O:36]CC)=[O:35])[CH3:29])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1.[OH-].[K+]>C(O)C>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([N:8]([CH:17]([CH3:21])[C:18]([N:30]([CH:28]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[CH3:29])[CH2:31][CH2:32][CH2:33][C:34]([OH:36])=[O:35])=[O:20])[C:9]1[CH:10]=[CH:11][C:12]([O:13][CH3:14])=[CH:15][CH:16]=1)=[O:7]

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 20292073HCID 20292073, compoundHCID 20292243HCID 20292243, compound

Product 1

HCID 20292149HCID 20292149, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(2-furoyl)-2-(p-anisidino)propionic acid and ethyl 4-(1-phenylethylamino)butyrate and suitable processing, dissolving the evaporation residue in ethanol, adding an ethanolic solution of potassium hydroxide, stirring for 12 hours at room temperature and further processing yields N-[N-(2-furoyl)-2-(p-anisidino)propionyl]-4-(1-phenylethylamino)butyric acid.

Sources & evidence

ORD record
ord-a0f06621b6294eeba3953bd7304957ce
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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