1-Bromopropane → HCID 178460806, compound

Participants

Reaction Steps

20.2 g. of 3-mercapto-1,2,4-triazole was added to a solution of 4.8 g. sodium in 150 ml. absolute ethanol. When dissolution was complete 24.6 g. propyl bromide was added. The stirred mixture was gradually heated to boiling under reflux, refluxed for 1 hour, cooled to room temperature and filtered. The filtrate was distilled to dryness under reduced pressure and the residue dissolved in ether. The resulting solution was filtered, dried over anhydrous sodium sulphate and distilled under reduced pressure to give 3-propylthio-1,2,4-triazole, b.p. 143°-144° C./1 mm. This product solidified, m.p. 53°-56° C.

Provenance & Evidence