反应详情

A slurry of methyl 4-chloro-α-methoxy-5-nitro-o-toluate (7.0 g.) in dilute sodium hydroxide (35 ml of IN) is stirred about 30 hours. The yellow slurry is then diluted with 50 ml. of water resulting in a clear yellow solution. The solution is extracted with ether, then the aqueous layer is separated and acidified to give 5.7 g. of an off-white solid. A sample recrystallized from benzene has a mp 155°-157°.

1. additionThe yellow slurry is then diluted with 50 ml
2. extractionThe solution is extracted with ether
3. customthe aqueous layer is separated
4. customto give 5.7 g
5. customA sample recrystallized from benzene