2-Methoxyaniline → HCID 20290817, compound

HRID 1413817Notes

Reaction equation

HRID 1413817 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[O:8][CH3:9].[CH:10]([F:17])([F:16])[C:11]([CH:13]([F:15])[F:14])=[O:12]>>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:11]([OH:12])([CH:10]([F:17])[F:16])[CH:13]([F:15])[F:14])=[CH:4][C:3]=1[O:8][CH3:9]

Participants

3

Reactant 2

HCID 70002-MethoxyanilineHCID 677582-Propanone, 1,1,3,3-tetrafluoro-

Product 1

HCID 20290817HCID 20290817, compound

Procedure

The procedure of Example 4 is used with 2-amino-methoxybenzene and sym-tetrafluoroacetone to give 4-amino[2,2-difluoro-1-hydroxy-1-(difluoromethyl)ethyl]-3-methoxybenzene.

Sources & evidence

ORD record
ord-4d725c7f49504fb68455cb2f8cbd6a4a
Source dataset
uspto-grants-1981_02
Patent number
US04251534

Reaction notes

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