Thiophenol → HCID 70577630, compound

Participants

Reaction Steps

A mixture of 8.8 g. (0.05 mole) of 1-benzyl-3,4-epoxypyrrolidine, 6.0 g. (0.055 mole) of thiophenol, and 3 drops of water was heated on a steam bath overnight. Upon cooling the mixture, a solid crystallized. The solid was dissolved in methylene chloride and the methylene chloride solution was washed with two 50-ml portions of 5% sodium hydroxide. The methylene chloride layer was dried over anhydrous sodium sulfate and concentrated to give a yellow oil which solidified on standing. The solid was recrystallized from cyclohexane to give 8.6 g. (60%) of a tan solid, m.p. 97°-99°.

Provenance & Evidence