HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Cyanide → 2-(p-Prenylphenyl)propionitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | 1-Chloro-1-(p-prenylphenyl)ethane | HCID 13291973 | — |
| Product | 2-(p-Prenylphenyl)propionitrile | HCID 13585023 | 81.8% |
Reaction Steps
A mixture of 21.0 g of 1-chloro-1-(p-prenylphenyl)ethane, 11.3 g of sodium cyanide and 140 ml of dimethylsufoxide was stirred at 60°-65° C. for 7 hours. After cooling, 400 g of ice-water was added and the resulting solution was extracted with n-hexane. The extract was washed with water, concentrated and distilled to give 16.4 g of 2-(p-prenylphenyl)propionitrile, b.p. 108-110 °C/0.28 mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04251543 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-74133b1a0cac4a999e37fac10338a28c |
| Source note | uspto-grants-1981_02 |