2,2'-Isopropylidene bis(4-fluorophenol) → 2-(5-Chloro-2-hydroxyphenyl)-2-(5-fluoro-2-hydroxyphenyl)propane

HRID 1413859Notes

Reaction equation

HRID 1413859 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:20])=[C:6]([C:8]([C:11]2[CH:16]=[C:15]([F:17])[CH:14]=[CH:13][C:12]=2[O:18]C)([CH3:10])[CH3:9])[CH:7]=1.C(C1C=C(F)C=CC=1O)(C1C=C(F)C=CC=1O)(C)C>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:20])=[C:6]([C:8]([C:11]2[CH:16]=[C:15]([F:17])[CH:14]=[CH:13][C:12]=2[OH:18])([CH3:10])[CH3:9])[CH:7]=1

Participants

3

Reactant 2

HCID 202910962,2'-Isopropylidene bis(4-fluorophenol)HCID 202911172-(5-Chloro-2-hydroxyphenyl)-2-(5-fluoro-2-methoxyphenyl)propane

Product 1

HCID 202911062-(5-Chloro-2-hydroxyphenyl)-2-(5-fluoro-2-hydroxyphenyl)propane

Procedure

2-(5-chloro-2-hydroxyphenyl)-2-(5-fluoro-2-hydroxyphenyl)propane (m.p. 125° C.) was prepared from 2-(5-chloro-2-hydroxyphenyl)-2-(5-fluoro-2-methoxyphenyl)propane following the method described in Example 3 for the preparation of 2,2'-isopropylidene bis(4-fluorophenol).

Sources & evidence

ORD record
ord-163152202ee44a2db8c560c37e2819cc
Source dataset
uspto-grants-1981_02
Patent number
US04251546

Reaction notes

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