HRID1413903

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7918

Acetic anhydride

C4H6O3

HCID19382815

N~1~,N~1~,N~3~,N~3~-Tetraethylbenzene-1,3-diamine

C14H24N2

结构：CCCCCCCCn1c(C)c(C(=O)c2ccccc2C(=O)O)c2ccccc21

HCID19763802

2-(2-Methyl-1-octyl-1H-indole-3-carbonyl)benzoic acid

C25H29NO3

PRODUCTS

生成物

结构：CCCCCCCCn1c(C)c(C2(c3ccc(N(CC)CC)cc3N(CC)CC)OC(=O)c3ccccc32)c2ccccc21

HCID20523552

未命名化合物

PROCEDURE

实验过程

Proceeding in a manner similar to that described in part B of Example 5 above, 2.34 g (0.006 mole) of 2-[(1-n-octyl-2-methyl-3-indolyl)carbonyl]benzoic acid prepared according to Example 5, part A, and 2.40 g of N,N,N',N'-tetraethyl-m-phenylenediamine were interacted in the presence of 2.40 g of acetic anhydride to obtain 3-[2,4-bis(diethylamino)phenyl]-3-(1-n-octyl-2-methyl-3-indolyl)phthalide (Formula III: R0 =R1 =R2 =R3 =Y1 =H; R=CH2CH3 ; R4 =N(CH2CH3)2 ; R5 =CH3 ; R6 =(CH2)7CH3) as a tar-like semisolid. A toluene solution of this material developed a purple color when spotted on silica gel.

WORKUP

后处理

customprepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9e9c15277fbf407ab40767289b29fc83
来源数据集: uspto-grants-1981_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04251446
来源说明: uspto-grants-1981_02

反应 SMILES

[CH2:1]([N:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]([C:18]([C:20]2[CH:28]=[CH:27][CH:26]=[CH:25][C:21]=2[C:22]([OH:24])=O)=[O:19])=[C:10]1[CH3:29])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[CH2:30]([N:32]([CH2:44][CH3:45])[C:33]1[CH:38]=[CH:37][CH:36]=[C:35]([N:39]([CH2:42][CH3:43])[CH2:40][CH3:41])[CH:34]=1)[CH3:31].C(OC(=O)C)(=O)C>>[CH2:40]([N:39]([CH2:42][CH3:43])[C:35]1[CH:34]=[C:33]([N:32]([CH2:30][CH3:31])[CH2:44][CH3:45])[CH:38]=[CH:37][C:36]=1[C:18]1([C:11]2[C:12]3[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=3)[N:9]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[C:10]=2[CH3:29])[C:20]2[C:21](=[CH:25][CH:26]=[CH:27][CH:28]=2)[C:22](=[O:24])[O:19]1)[CH3:41]