Hydrochloric Acid → 2,5-Bis[4-(p-aminostyryl)phenyl]-1,3,4-oxadiazole

Participants

Reaction Steps

After mixing 6.0 g of 2,5-bis[4-(p-nitrostyryl)phenyl]-1,3,4-oxadiazole, 12.0 g of iron powder and 200 g of N,N-dimethyl formamide together, by adding dilute hydrochloric acid prepared by employing 5 ml of undiluted hydrochloric acid and 17 ml of water to the resulting mixture and intensely stirring it, reaction was effected at a temperature of 90° to 100° C. for one hour. After completing the reaction, by adding a 5% aqueous solution of sodium carbonate while heating as above, the pH value of the reactant mixture was adjusted to be 8, the undissolved matter was filtered while heating, and the resulting filtrate was diluted with 70 ml of water, whereby there were separated yellow crystals. Then, said crystals were collected by filtering, washed in water and dried, whereby there were obtained 5.0 g (yield rate: 94.3%) of 2,5-bis[4-(p-aminostyryl)phenyl]-1,3,4-oxadiazole. The melting point of this crystal was 250° C. or more (decomposition point).

Provenance & Evidence