Acetic Anhydride → HCID 54238830, compound

HRID 1413933Notes

Reaction equation

HRID 1413933 reaction equation
[O:1]([C:8]1[CH:9]=[C:10]([CH2:15][OH:16])[N+:11]([O-])=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:17](OC(=O)C)(=[O:19])[CH3:18]>>[C:17]([O:16][CH2:15][C:10]1[CH:9]=[C:8]([O:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH:13]=[CH:12][N:11]=1)(=[O:19])[CH3:18]

Participants

3

Reactant 2

HCID 7918Acetic Anhydride2×HCID 20291303HCID 20291303, compound

Product 1

HCID 54238830HCID 54238830, compoundYield 88%

Procedure

All of the 4-phenoxypyridine-2-methanol-N-oxide was added to 45.0 g of acetic anhydride and the mixture was refluxed for 15 minutes to react them. After the reaction, acetic anhydride and the by-product of acetic acid were distilled off under a reduced pressure and the resulting crude product was distilled under a reduced pressure to obtain 40 g of the object compound (yield: 88%).

Workup

  1. temperaturethe mixture was refluxed for 15 minutes
  2. customto react them
  3. distillationthe by-product of acetic acid were distilled off under a reduced pressure
  4. distillationthe resulting crude product was distilled under a reduced pressure

Sources & evidence

ORD record
ord-c2674438b5854d569c9b55dca4df4131
Source dataset
uspto-grants-1981_02
Patent number
US04251662

Reaction notes

Loading…