3-(4-Trifluoromethylphenyl)-4-isopropyloxazolidine-2,5-dione → 3-Benzylpyrrolylmethyl 2-(4-trifluoromethylphenylamino)-3-methylbutanoate

HRID 1413971Notes

Reaction equation

HRID 1413971 reaction equation
[F:1][C:2]([F:20])([F:19])[C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH:13]([CH:14]([CH3:16])[CH3:15])[C:12](=[O:17])[O:11][C:10]2=O)=[CH:5][CH:4]=1.[CH2:21]([C:28]1[CH:32]=[CH:31][NH:30][C:29]=1CO)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[F:1][C:2]([F:20])([F:19])[C:3]1[CH:8]=[CH:7][C:6]([NH:9][CH:13]([CH:14]([CH3:16])[CH3:15])[C:12]([O:11][CH2:10][C:29]2[NH:30][CH:31]=[CH:32][C:28]=2[CH2:21][C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)=[O:17])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 204827863-(4-Trifluoromethylphenyl)-4-isopropyloxazolidine-2,5-dioneHCID 543430813-Benzyl-1-pyrrolylmethanol

Product 1

HCID 202893013-Benzylpyrrolylmethyl 2-(4-trifluoromethylphenylamino)-3-methylbutanoate

Procedure

In the same way, 3-(4-trifluoromethylphenyl)-4-isopropyloxazolidine-2,5-dione is reacted with 3-benzylpyrrolylmethyl alcohol to give 3-benzylpyrrolylmethyl 2-(4-trifluoromethylphenylamino)-3-methylbutanoate.

Sources & evidence

ORD record
ord-592dcaba557a4dbea7c369e298a9981d
Source dataset
uspto-grants-1981_02
Patent number
US04252724

Reaction notes

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