2-((4-Fluorophenyl)amino)-3-methylbutanoic acid → 3-Benzylpyrrolylmethyl 2-(4-fluorophenylamino)-3-methylbutanoate

HRID 1413972Notes

Reaction equation

HRID 1413972 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][CH:9]([CH:13]([CH3:15])[CH3:14])[C:10]([OH:12])=[O:11])=[CH:4][CH:3]=1.[CH2:16]([C:23]1[CH:27]=[CH:26][NH:25][C:24]=1[CH2:28]O)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][CH:9]([CH:13]([CH3:15])[CH3:14])[C:10]([O:12][CH2:28][C:24]2[NH:25][CH:26]=[CH:27][C:23]=2[CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:11])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 204827962-((4-Fluorophenyl)amino)-3-methylbutanoic acidHCID 543430813-Benzyl-1-pyrrolylmethanol

Product 1

HCID 202892923-Benzylpyrrolylmethyl 2-(4-fluorophenylamino)-3-methylbutanoate

Procedure

The acid 2-(4-fluorophenylamino)-3-methylbutanoic acid is reacted with 3-benzylpyrrolylmethyl alcohol using the procedure of Example 3 to give 3-benzylpyrrolylmethyl 2-(4-fluorophenylamino)-3-methylbutanoate.

Sources & evidence

ORD record
ord-bdf0190b37e84e73a600bd1420e333a2
Source dataset
uspto-grants-1981_02
Patent number
US04252724

Reaction notes

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