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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1413974Generated: October 31, 2026

2-(2-Fluoro-4-trifluoromethylphenylamino)-3-methylbutanoic acid → 3-(3-Fluorobenzyl)-pyrrolylmethyl 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoate

https://huagongshe.com/reaction/1413974

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Fluoro-4-trifluoromethylphenylamino)-3-methylbutanoic acidHCID 20283983—
Reactant3-(3-Fluorobenzyl)-pyrrolylmethyl alcoholHCID 54523279—
Product3-(3-Fluorobenzyl)-pyrrolylmethyl 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoateHCID 20289296—

Reaction Steps

The acid chloride of 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoic acid is reacted with 3-(3-fluorobenzyl)-pyrrolylmethyl alcohol using the procedure of Example 1 to give 3-(3-fluorobenzyl)-pyrrolylmethyl 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04252724
Source datasetuspto-grants-1981_02
ORD IDord-da00b588098340c19db3706f73ae57a3
Source noteuspto-grants-1981_02