反应详情

Employing a reaction similar to that described in Example 1 except that a hydrocarbon solvent is included in the reaction mixture, 152 g 50% aqueous potassium hydroxide solution was added dropwise to a vigorously stirred solution of 64.5 g (0.52 mol) trans 1,4-dichlorobutene-2,112.5 g (0.52 mol) di-n-butyl malonate, 4.0 g tricaprylylmethylammonium chloride and 200 cc petroleum ether. Upon workup and distillation, 47.6 g (37.1% yield) of di-n-butyl 2-vinylcyclopropane-1,1-dicarboxylate (bp 101°-104° C. (0.30 mm)); nD24° 1.4556) was obtained. Infrared and proton nmr spectra were consistent with th desired vinylcyclopropane product. Attempts to carry out the reaction in the absence of the onium compound were unsuccessful.

1. customa reaction similar to