Benzyl Alcohol → HCID 20289409, compound

Participants

Reaction Steps

An amount of 125 g of benzyl alcohol is stirred and 0.3 g of finely cut sodium metal (0.013 mole) is added and the mixture then stirred under nitrogen for 2.5 hours. Then with stirring, 27.79 g of N,N-bis(2,3-epoxypropyl)benzylamine (0.15 mole) is added to the reaction mixture and stirring at room temperature continued for 0.5 hour, followed by heating the mixture at reflux for 16 hours. The mixture is then cooled to room temperature and poured into 400 ml of water. The aqueous mixture is extracted with 2×250 ml portions of chloroform, and the CHCl3 extracts are combined and dried over anhydrous sodium sulfate. The CHCl3 is removed in vacuo and the colorless oil vacuum distilled through a 10 cm vigreux distilling column. The fraction distilling at b.p. 196°-199° @0.4 mm is collected yielding 28.6 g (65%) of the title compound.

Provenance & Evidence