Triethylamine → HCID 86737511, compound

Participants

Reaction Steps

A solution of 1-[(diphenylamino)carbonyl]pyridinium chloride (1.1 g) in water (10 ml) was added rapidly to a stirred solution of 3-[2-[[(phenylmethoxy)carbonyl]amino]ethyl]-1H-indole-5-carboxylic acid (1 g) and triethylamine (0.6 ml) in water (15 ml). After 0.5 hour, an amorphous yellow solid (1.7 g) was filtered off. A sample (0.5 g) was crystallised from a mixture of ethyl acetate and cyclohexane to give the title compound (0.3 g) as a cream crystalline solid m.p. 137°-138.5° C.

Provenance & Evidence