Acetone → 2,2,6,6-Tetramethyl-4-piperidone

Participants

Reaction Steps

A flask with attached condenser was charged with 80 g of acetonine, 80 g of acetone, 16 g methanol and 1.6 g N-phenylhydrazine monohydrochloride and the mixture reacted at 50°-55° C. for 18 hours, while stirring. The reaction solution was stripped under reduced pressure, to obtain a light red residue. This residue was distilled in vacuo to obtain 60.4 g of triacetonamine. White crystals were obtained by recrystallization from petroleum ether having the melting point of 34°-36° C. The compound was confirmed to be the objective matter by IR spectrum and gas chromatography.

Provenance & Evidence