Acetone → 2,2,6,6-Tetramethyl-4-piperidone

Participants

Reaction Steps

80 g of acetonine, 580 g of acetone, 24 g of water and 1.9 g of N-phenylhydrazine hydrochloride were reacted at 50°-55° C. for 3 hours. Then, 50 g of acetonine and 1.3 g of catalyst were added to the reaction solution and reacted for 3 hours. This procedure was repeated twice and the last addition of acetonine and catalyst the reaction was continued for 10 hours at the same temperature and obtained 185.2 g of triacetonamine after stripping and vacuum distillation.

Provenance & Evidence