Methyl iodide → HCID 21415702, compound

HRID 1414150Notes

Reaction equation

HRID 1414150 reaction equation
[CH3:1][C:2]1[C:11]([CH3:12])=[N:10][C:9]2[C:4](=[CH:5][C:6]([O:15][CH3:16])=[C:7]([O:13][CH3:14])[CH:8]=2)[N:3]=1.[CH3:17][I:18]>>[I-:18].[CH3:17][N+:10]1[C:9]2[C:4](=[CH:5][C:6]([O:15][CH3:16])=[C:7]([O:13][CH3:14])[CH:8]=2)[N:3]=[C:2]([CH3:1])[C:11]=1[CH3:12]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 30823426,7-Dimethoxy-2,3-dimethylquinoxaline

Product 1

HCID 21415702HCID 21415702, compound

Conditions

Temperature
100 °C

Procedure

5.5 g (0.025 mol) of 2,3-dimethyl-6,7-dimethoxyquinoxaline are dissolved in 30 ml of methyl iodide in a 100 ml stirred autoclave. This solution is warmed to 100°C for 24 hours whilst stirring, in the course of which the pressure rises to about 7 atmospheres gauge. After cooling to room temperature, the yellow precipitate is filtered off, rinsed with a little dry acetone and dried. Yield about 6.5 g, corresponding to 72% of theory. Melting point 210° to 212°C (decomposition). The IR (KBr) and NMR (DMSO-d6) spectrum agree with the postulated structure.

Workup

  1. stirringwhilst stirring, in the course of which the pressure
  2. temperatureAfter cooling to room temperature
  3. filtrationthe yellow precipitate is filtered off
  4. washrinsed with a little dry acetone
  5. customdried

Sources & evidence

ORD record
ord-cf2989478c9a45ad8f9d48b361362396
Source dataset
uspto-grants-1977_01
Patent number
US04001017

Reaction notes

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