4-Aminobenzoic Acid → 4-[Bicyclo-(2,2,1)hept-2-yl-acetamido]-benzoic acid
Reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[CH:11]12[CH2:17][CH:14]([CH2:15][CH2:16]1)[CH2:13][CH:12]2[CH2:18][C:19](Cl)=[O:20]>>[CH:11]12[CH2:17][CH:14]([CH2:15][CH2:16]1)[CH2:13][CH:12]2[CH2:18][C:19]([NH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1)=[O:20]Participants
3
Procedure
4-[Bicyclo-(2,2,1)hept-2-yl-acetamido]-benzoic acid was prepared as described in Example 3 from 9.63 g (0.07 mol) of p-aminobenzoic acid and 13.2 g (0.077 mol) of bicyclo(2,2,1)hept-2-yl-acetyl chloride.
Sources & evidence
- ORD record
- ord-de1ae2e4373d45eca3f5e6d6d42b6ea0
- Source dataset
- uspto-grants-1977_01
- Patent number
- US04001218
Reaction notes
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