4-Aminosalicylic Acid → HCID 16775697, compound

HRID 1414196Notes

Reaction equation

HRID 1414196 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([OH:11])[CH:3]=1.[CH:12]1([C:17](Cl)=[O:18])[CH2:16][CH2:15][CH2:14][CH2:13]1>>[CH:12]1([C:17]([NH:1][C:2]2[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([OH:11])[CH:3]=2)=[O:18])[CH2:16][CH2:15][CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 46494-Aminosalicylic AcidHCID 78284Cyclopentanecarbonyl chloride

Product 1

HCID 16775697HCID 16775697, compound

Procedure

4-Cyclopentanecarbonylamino-2-hydroxy-benzoic acid was prepared as described in Example 3 from 8 g (0.0379 mol) of 4-amino-2-hydroxy-benzoic acid (sodium salt, with 2 mols of H2O) and 5.28 g (0.0398 mol) of cyclopentanecarboxylic acid chloride.

Sources & evidence

ORD record
ord-54685724066444e5902f654bb28562a7
Source dataset
uspto-grants-1977_01
Patent number
US04001218

Reaction notes

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