HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 1-(Chloromethyl)adamantane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Tricyclo(3.3.1.1'3,7)dec-1-ylmethanol | HCID 64556 | — |
| Reactant | 1-(Bromomethyl)adamantane | HCID 1416304 | — |
| Catalyst | Zincchloride | HCID 3007855 | — |
| Catalyst | Zinc bromide | HCID 10421208 | — |
| Product | 1-(Chloromethyl)adamantane | HCID 2103969 | 91% |
Reaction Steps
Chlorination reaction of 1-adamantyl methylalcohol which was obtained by the same method described in (1) was carried out under the same conditions for the bromination reaction shown in (2) except that zinc bromide and hydrobromic acid were replaced by zinc chloride and hydrochloric acid respectively. The product was purified by recrystallized from methanol. Melting point of 1-adamantyl methyl chloride thus obtained was 32°-34° C and the yield was 91%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04001223 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-fbbd2f48596345ff98bd1e3f739e32b8 |
| Source note | uspto-grants-1977_01 |