Picolyl chloride → 2-(Methoxymethyl)pyridine

HRID 1414248Notes

Reaction equation

Cl[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.[CH3:9][O-:10].[Na+]>>[CH3:9][O:10][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1

Participants

Reactant 2

HCID 23393Picolyl chloride

HCID 10942334Sodium Methoxide

Product 1

HCID 2532202-(Methoxymethyl)pyridine

Procedure

Alternatively, 0.1 mole of 2-(chloromethyl)pyridine and 0.11 mole of sodium methoxide are used in the above procedure to give 2-(methoxymethyl)pyridine.

Sources & evidence

ORD record: ord-173dc3e7f0ff4dfcaddc643bd2cea295
Source dataset: uspto-grants-1977_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04001241

Reaction notes

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