HCID 11110673, compound → HCID 21486956, compound

HRID 1414275Notes

Reaction equation

HRID 1414275 reaction equation
[CH2:1]([O:8][C:9]1[CH:18]=[C:17]2[C:12]([CH2:13][CH2:14][N:15]=[C:16]2[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:11][C:10]=1[O:25][CH3:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC1C=C2C(=CC=1OC)C(C1C=CC=CC=1)=NCC2)C1C=CC=CC=1>>[CH2:1]([O:8][C:9]1[CH:18]=[C:17]2[C:12]([CH2:13][CH2:14][NH:15][CH:16]2[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)=[CH:11][C:10]=1[O:25][CH3:26])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 11110673HCID 11110673, compoundHCID 21487019HCID 21487019, compound

Product 1

HCID 21486956HCID 21486956, compound

Procedure

Substitution of a like quantity of 7-benzyloxy-6-methoxy-1-phenyl-3,4-dihydroisoquinoline for the 6-benzyloxy-7-methoxy-1-phenyl-3,4-dihydroisoquinoline used above and substantial repetition of the foregoing procedure affords 7-benzyloxy-6-methoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline, melting at about 123°-125°C.

Sources & evidence

ORD record
ord-478ee15de149425e8e7ec490dd8de2c6
Source dataset
uspto-grants-1977_01
Patent number
US04001244

Reaction notes

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