1,2-Ethanediamine, N1,N1-bis(1-methylethyl)- → HCID 21487005, compound

HRID 1414279Notes

Reaction equation

HRID 1414279 reaction equation
[CH:1]([N:4]([CH:8]([CH3:10])[CH3:9])[CH2:5][CH2:6][NH2:7])([CH3:3])[CH3:2].C(N(CC)CCN[C:17]([N:19]1[CH2:28][CH2:27][C:26]2[C:21](=[CH:22][C:23]([O:31][CH3:32])=[C:24]([O:29][CH3:30])[CH:25]=2)[CH:20]1[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)=[O:18])C>>[CH:1]([N:4]([CH:8]([CH3:10])[CH3:9])[CH2:5][CH2:6][NH:7][C:17]([N:19]1[CH2:28][CH2:27][C:26]2[C:21](=[CH:22][C:23]([O:31][CH3:32])=[C:24]([O:29][CH3:30])[CH:25]=2)[CH:20]1[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)=[O:18])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 84591,2-Ethanediamine, N1,N1-bis(1-methylethyl)-HCID 21486957HCID 21486957, compound

Product 1

HCID 21487005HCID 21487005, compound

Procedure

Substitution of an equivalent quantity of 2-diisopropylaminoethylamine for the 2-diethylaminoethylamine used above and substantial repetition of the foregoing procedure affords N-(2-diisopropylaminoethyl)-6,7-dimethoxy-1-phenyl-3,4-dihydro-2(1H)-isoquinolinecarboxamide, melting at about 109°-110°C.

Sources & evidence

ORD record
ord-91855161a84e47bf81c684dc02fbfa43
Source dataset
uspto-grants-1977_01
Patent number
US04001244

Reaction notes

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