1,2-Ethanediamine, N1,N1,N2-trimethyl- → HCID 21486961, compound

HRID 1414281Notes

Reaction equation

HRID 1414281 reaction equation
[CH3:1]N(C)CCNC.[CH:8]([N:11]([CH:39](C)C)[CH2:12][CH2:13][NH:14][C:15]([N:17]1[CH2:26][CH2:25][C:24]2[C:19](=[CH:20][C:21]([O:29][CH3:30])=[C:22]([O:27][CH3:28])[CH:23]=2)[CH:18]1[C:31]1[CH:36]=[CH:35][C:34]([O:37][CH3:38])=[CH:33][CH:32]=1)=[O:16])(C)C>>[CH3:28][O:27][C:22]1[CH:23]=[C:24]2[C:19](=[CH:20][C:21]=1[O:29][CH3:30])[CH:18]([C:31]1[CH:32]=[CH:33][C:34]([O:37][CH3:38])=[CH:35][CH:36]=1)[N:17]([C:15]([N:14]([CH2:13][CH2:12][N:11]([CH3:39])[CH3:8])[CH3:1])=[O:16])[CH2:26][CH2:25]2

Participants

3

Reactant 2

HCID 673381,2-Ethanediamine, N1,N1,N2-trimethyl-HCID 21486984HCID 21486984, compound

Product 1

HCID 21486961HCID 21486961, compound

Procedure

Substitution of an equivalent quantity of N,N,N'-trimethylethylenediamine for the 2-diisopropylaminoethylamine used above and substantial repetition of the foregoing procedure affords 6,7-dimethoxy-N-(2-dimethylaminoethyl)-1-(4-methoxyphenyl)-N-methyl-3,4-dihydro-2(1H)-isoquinolinecarboxamide.

Sources & evidence

ORD record
ord-3f04617910424c2797e61f10fc3262b2
Source dataset
uspto-grants-1977_01
Patent number
US04001244

Reaction notes

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