HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-6-fluoro-2-methylquinoline → 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-6-fluoro-2-methylquinoline | HCID 87694 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Product | 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline | HCID 591684 | — |
Reaction Steps
4-Chloro-6-fluoroquinaldine was reduced with rhodium on carbon to give 6-fluoro-2-methyltetrahydroquinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04001243 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-98ea57f3141c49fd96fc631639df7059 |
| Source note | uspto-grants-1977_01 |