HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Isopropanol → Diethyl 2-amino-4,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Isopropanol | HCID 3776 | — |
| Edukt | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| Edukt | Ethylideneacetoacetic acid ethyl ester | HCID 53428592 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | Diethyl 2-amino-4,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate | HCID 12391086 | 59% |
Reaktionsschritte
Upon heating a solution of ethylideneacetoacetic acid ethyl ester and 13.0 g of amidinoacetic acid ethyl ester in 100 ml of ethanol for 2 hours, 2-amino-4,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of melting point 140°C (isopropanol) is obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04001258 |
| Quelldatensatz | uspto-grants-1977_01 |
| ORD ID | ord-0e439da5b51446769fad05c5774a3c24 |
| Quellennotiz | uspto-grants-1977_01 |