反应详情

33.6 parts of 2,4,5-trimethylbenzophenone and 0.1 part of iodine are dissolved in 150 parts of trichloroethylene. 19.2 parts of chlorine is passed into this solution at 0° to 5°C over a period of 3 hours. The mixture is stirred for another 5 hours at ambient temperature and then distilled at subatmospheric pressure. 26 parts (67.2% of theory) of 3-chloro-2,4,5-trimethylbenzophenone is obtained at 155° to 165°C at 0.1 mmHg.

1. distillationdistilled at subatmospheric pressure