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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1414490Generated: October 27, 2026

1-(4-Chlorobutyl)-1-Ethyl-7-Methoxy-2-Tetralone → 5-Ethyl-6,7,8,9,10,11-Hexahydro-3-Methoxy-5,10-Methano-5H-Benzocyclononen-12-One

https://huagongshe.com/reaction/1414490

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chlorobutyl)-1-Ethyl-7-Methoxy-2-TetraloneHCID 21410117—
Reactant6,7,8,9,10,11-hexahydro-3-methoxy-5-methyl-5,10-methano-5H-benzocyclononen 12-oneHCID 21410123—
Product5-Ethyl-6,7,8,9,10,11-Hexahydro-3-Methoxy-5,10-Methano-5H-Benzocyclononen-12-OneHCID 21410072—

Reaction Steps

Using a procedure analogous to that described in Example X for the preparation of 6,7,8,9,10,11-hexahydro-3-methoxy-5-methyl-5,10-methano-5H-benzocyclononen-12-one there is obtained from 37.4 g. of 1-(4-chlorobutyl)-1-ethyl-7-methoxy-2-tetralone, 22.2 g. of the title product, b.p. 138° to 142° C. (0.35 mm.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04001326
Source datasetuspto-grants-1977_01
ORD IDord-cca0321c02f247e7955ed792508d89ce
Source noteuspto-grants-1977_01