HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Clobazam
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Desmethylclobazam | HCID 89657 | — |
| Product | Clobazam | HCID 2789 | — |
Reaction Steps
Starting from 1-phenyl 8-chloro 1,2,4,5-tetrahydro 2,4-dioxo 3H-1,5-benzodiazepine (obtained according to the example XI) and from a methyl halide, and operating according to the example X, there is obtained 1-phenyl 5-methyl 8-chloro 1,2,4,5-tetrahydro 2,4-dioxo 3H-1,5-benzodiazepine, melting at 166°-168° C after recristallisation in 50% ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04001408 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-7181366743ec45ee8cf448ea93b5480a |
| Source note | uspto-grants-1977_01 |