Hydrochloric Acid → HCID 23460506, compound

Participants

Reaction Steps

5-Methoxy-2-nitroxanthone (5.0 g.) is added in small portions during 30 minutes to a stirred mixture of stannous chloride dihydrate (30 g.) and concentrated hydrochloric acid (30 ml.) heated on a steam-bath. The mixture is stirred and heated on a steam-bath for a further 2 hours. The precipitate is filtered off, washed with water and stirred with 5N sodium hydroxide solution (50 ml.) for 1 hour. The solid is filtered off, made into a slurry with methanol and treated with ethereal hydrochloric acid. The solid is crystallised from methanol-ether to give 2-amino-5-methoxyxanthone hydrochloride, m.p. 271°-273° C.

Provenance & Evidence