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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1414597Generated: November 5, 2026

Tert-Butylamine → 2-Bromo-4-t-butylaminocarbonylthiazole

https://huagongshe.com/reaction/1414597

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-ButylamineHCID 6385—
Reactant2-Bromo-1,3-thiazole-4-carboxylic acidHCID 2763209—
Product2-Bromo-4-t-butylaminocarbonylthiazoleHCID 15663804—

Reaction Steps

Similarly, 2-bromo-4-t-butylaminocarbonylthiazole is prepared by following the same procedure but using 2-bromo-4-carboxythiazole in place of the 5-position isomer. Similarly, by replacing t-butylamine with the amine reagents set forth in Preparation 2, the corresponding 2-bromo-4- and 5-substituted aminocarbonylthiazoles are respectively prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04001421
Source datasetuspto-grants-1977_01
ORD IDord-f7c6e668391a44b49ddd76eaa01c5de4
Source noteuspto-grants-1977_01