Potassium Carbonate → 2-[4'-(2,3-Epoxypropoxy)phenyl]-3-(4'-methylbenzoyl)benzofuran

Participants

Reaction Steps

A mixture of 2.0 g. (6.1 mmol.) of 2-p-hydroxyphenyl-3-p-methylbenzoylbenzofuran, 2.6 g. (0.019 mol.) of epibromohydrin and 3.0 g. (0.021 mol.) of potassium carbonate in 100 ml. of dry acetone was refluxed for 12 hours. After cooling, the reaction mixture was filtered and the filtrate was concentrated to give 2-[4'-(2,3-epoxypropoxy)phenyl]-3-(4'-methylbenzoyl)benzofuran.

Provenance & Evidence